产品货号：
Z23377
中文名称：
p53R2/RRM2B抗体
英文名称：
Anti-p53R2/RRM2B Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-p53R2/RRM2B Antibody |
| 指标别名 | p53R2;RRM2B;RRM2B;p53R2 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | RRM2B |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human p53R2(318-332aa EGKTNFFEKRVSEYQ),identical to the related rat and mouse sequences. |
| 实际分子量 | 39KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RRM2B(Ribonucleotide Reductase,M2 B),also known as P53R2,is an enzyme that in humans is encoded by the RRM2B gene.Tanaka et al.(2000) mapped the p53R2 gene to chromosome 8q23.1 by fluorescence in situ hybridization.Tanaka et al.(2000) found that expression of p53R2,but not R2,was induced by ultraviolet and gamma-irradiation and adriamycin treatment in a wildtype p53-dependent manner.Induction of p53R2 in p53-deficient cells caused G2/M arrest and protected cells from death in response to adriamycin.Inhibition of endogenous p53R2 expression in cells that had an intact p53-dependent DNA damage checkpoint reduced ribonucleotide reductase activity,DNA repair,and cell survival after exposure to various genotoxins. |
| Uniprot ID | Q7LG56 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | ribonucleotide reductase M2 B(TP53 inducible) |
| 蛋白名全称 | Ribonucleoside-diphosphate reductase subunit M2 B |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
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